Using Warfarin with Diabetes Drugs May Elevate Risk Of Severe Hypoglycemia

“This study is of the medical records of 465,918 Medicare patients who filled prescriptions for warfarin and the sulfonylureas glipizide and glimepiride. This record analysis shows a substantial positive association was seen with the use of warfarin with glipizide/glimepiride and hospital admission/emergency department visits for hypoglycemia and related diagnoses, particularly in patients starting warfarin. The findings suggest the possibility of a significant drug interaction between these medications, Follow the link “study” for details.” Bill Chesnut, MD

 Using Warfarin with Diabetes Drugs May Elevate Risk Of Severe Hypoglycemia In Older Adults, Study Says

Medscape (12/22, Tucker) reports that a study published in the BMJ found that “concurrent use of warfarin and the diabetes drugs glipizide and glimepiride appears to dramatically elevate the risk for severe hypoglycemia in older adults.” Researchers say they found a “substantial positive association” between the use of the drugs and visits to the emergency department, hospital admissions due to hypoglycemia and fractures from falls.